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thefamilyman

04/28/15 1:06 PM

#99705 RE: To infinity and beyond! #99700

I had occasion to speak with the person in charge of intake at Dana Farber regarding my father. He asked me if my father had been diagnosed with a problem with p53. Apparently a lot of their patients are referred to the trial because their oncologist has determined that there is a problem with p53. It sounds like the patient pool may be heavy with those who have diagnosed problems with p53.

This deserved a reply, as did your critique of my critique of corporate update. (Off last week, little time to write)

I am surprised that they are not recruiting only those with p53 deletions. It does make any conclusions about efficacy very difficult now.

I still believe CTIX knows if the pts have p53 deletions or not, and that the company would shout from the rooftops if they could about early efficacy, but time will tell.

New dosing, new cohorts, new data, all in the works....

Still wish for preclinical data about K plus other combo treatments-ovarian lung brain breast etc
- To infinity and beyond!