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slcimmuno

04/27/15 9:14 PM

#99604 RE: To infinity and beyond! #99551

Perhaps not as long as one might think--seems like they've already got a good start, IDing lead compounds from their library of 1800 compounds. Building on B ought to help lots too.

Below link to RH Hancock out of U of BC... On immunodulatory antibiofilm properties of peptides (and by ext CTIXs nonpepditic mimics) ... More support of Host Defense-based ABXs.

http://eccmidlive.org/resources/antibiofilm-peptides-potential-as-a-broad-spectrum-agent

His 2006 study
http://www.cmdr.ubc.ca/bobh/rjpdocs/320_2006_NatureBiotech_24_p1551.pdf