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john1045

04/16/15 9:11 AM

#17925 RE: montanus #17924

Great find....interesting to point out Dr. Bradley Hyman as a co-author as well now aligned with ILNS on tau!

“These findings suggest that the combination of genetic, molecular and neuroimaging measures may be additionally helpful for detecting and quantifying the biochemical effects of therapeutic interventions,” said Anders M. Dale, PhD, professor of neurosciences and radiology and director of the Center for Translational Imaging and Precision Medicine at UC San Diego and the study’s senior author.
Co-authors include Andrew J. Schork, Linda K. McEvoy, Dominic Holland, James B. Brewer, Chi-Hua Chen, Wesley K. Thompson, UCSD; Yunpeng Wang, UCSD and Oslo University Hospital; Aree Witoelar, Ingun Dina Ulstein, Srdjan Djurovic, Oslo University Hospital, Norway; Manu Sharma, Thomas Gasser, University of Tubingen, Germany; Denise Harold, Julie Williams, Michael J. Owen, Michael C. O’Donovan, Cardiff University School of Medicine, Wales; Margaret A. Pericak-Vance, University of Miami; Richard Mayeux, Columbia University; Jonathan L. Haines, Vanderbilt University; Lindsay A. Farrer, Boston University Schools of Medicine and Public Health; Peter Heutink, German Center for Neurodegenerative Diseases; Andrew B. Singleton, Lenore Launer, National Institute on Aging; Alexis Brice, Sorbonne University; Nicolas Wood, John Hardy, University College London; Maria Martinez, INSERM; Seung Hoi Choi, Anita DeStefano, Boston University; M. Arfan Ikram, Cornelia van Juijn, Erasmus MC University Medical Center; Joshua C. Bis, Annette L. Fitzpatrick, University of Washington; Albert Smith, Icelandic Heart Association; Dag Aarsland, Karolinska Institute, Sweden; Tormod Fladby, Akershus University Hospital, Norway; Bradley T. Hyman, Massachusetts General Hospital; Jon Snaedal, University Hospital Reykjavik, Iceland; and Hreinn Stefanson, Kari Stefanson, University of Iceland.
Funding for this research came, in part, the National Institutes of Health (grants R01AG031224, K01AG029218, K02NS067427, T32 EB005970, UO1AG032984, U24-AG041689, and R01 MH100351), the Research Council of Norway, the South East Norway Health Authority, the Norwegian Health Association and the KG Jebsen Foundation.

www.healthcanal.com/brain-nerves/brain-diseases/alzheimer%E2%80%99s/60322-tau-associated-mapt-gene-increases-risk-for-alzheimer%E2%80%99s-disease.html