When asked about curing cancer with ONE drug, Richard Pazdur seemed to believe a cure will come from a combined therapy and they have built a committee and ate requesting ideas from many of the brilliant minds in oncology of what they think. That is COOL!
I would hope reactivating p53 would be a crucial "PART" in these combined therapies. I think that is where we can see so much value. It's a crucial step in fighting cancer and CTIX is a first to do so without being toxic!
And thanks for the PM too (can't reply privately as I'm currently in cheapskate mode).
For those who haven't had a look at these, the last video has some really interesting material about the approval pathway and how they're striving to cut out redundant safety testing for speedier approval. Hard to say when this may all "take effect" but it's great to see a change in the dogmatic thinking that has seemed to prevail in the FDA for so long. I've been asking about that in regard to the new IND HDP trials (starting at phase 2). It seems like maybe some of this streamlining is already occurring and not just in the area of oncology.