I draw a distinction between placebo patients thinking they improved on some subjective measure such as pain or anxiety and a verifiable improvement in an objective clinical metric (in this case confirmed by before-and-after liver biopsies).
Over time, NASH patients do sometimes get better on their own, and hence it’s cheating for Genfit to exclude a portion of the dataset from this trial because of such outcomes in the control arm.
>I thought that by definition the placebo is not "real" but the effect is. Therefore, isn't their usage correct?<
Wasn't it claimed that the placebo effect in the NASH score = 3 patients was a result of diet and exercise? If so then the same beneficial forces should have also been at work in the GFT-505 arms... but maybe less so for the more severe NASH patients.
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