Replies to post #94464 on Innovation Pharmaceuticals Inc (IPIX)

[slcimmuno]

Thx for the post - much appreciated Some Sunday reading for me post qt in the mtns

Here's a link to the Espinosa Lab at U Colorado -- all things P53

http://espinosalab.org/projects

[frrol]

Perhaps instead kevetrin should be combined with something that reduces p21

Perhaps not, since Kevetrin also induces PUMA, and apparently it is the PUMA/p21 ratio that matters. Great question.

[To infinity and beyond!]

It is very generous for you to take the time to point out those posts, which are very interesting and helpful. I would only say that the more I read about p53 p21 PUMA etc the less clear it all seems.

It is also interesting that Phase 1 for the Aprea drug was not impressive, and yet in combo with Cisplat it may be a winner.

That suggests of course that less than sterling phase 1 for Kevetrin is not the be all or end all, just a beginning.

Thanks again.