As I said in same post, next sentence, would not expect much fr early cohorts. And I agree that putting eggs in p21 basket maybe not wise since patient survival is what counts.
Let's see, a direct answer: half of pts increasing by 10%? What could be better than that? How about 2/3 increasing by 20 %? Or 3/4 increasing by 25% Or.......
None of it matters. All that matters is what is to come.