I share your appreciation of the great science Ariad has produced over the years. Like yourself I have been very patient but at this point it is clear that five more years of promises just isn't good enough. We need either a change of management, a buyout, or less preferably a major partnership or the standstill agreement advocated by civic for years. Personally I want to see Harvey out asap and replaced by whomever Denner decides to appoint while he negotiates an appropriate strategy. I am in it for the long haul but our forbearance shouldn't be mistaken for acceptance of Berger's ineptitude.