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scottsmith

02/12/15 8:04 PM

#91402 RE: To infinity and beyond! #91401

You say many are gambling. Please explain the difference between those who are and those who aren't.

F1ash

02/12/15 8:07 PM

#91403 RE: To infinity and beyond! #91401

I guess you have done zero research on Brilacidin then? That or you are being disingenuous.

MinnieM

02/12/15 8:13 PM

#91404 RE: To infinity and beyond! #91401

The Cellecutix share price jumped when Brilacidin QIDP designation was announced on December 8, 2014
http://cellceutix.com/cellceutix-antibiotic-brilacidin-receives-qidp-designation-from-fda/#sthash.IDhXbuGI.dpbs

It can be seen in the following chart.


Without the Brilacidin acquisition and trial results the shares would be priced much lower as investors tired of waiting on Kevetrin results.

As Brilacidin has been moving forward the share price has been moving forward. Brilacidin is further along in the trial process and has shown successful results.

Kevetrin is showing promise, but, the market won't price it in until trial results are in. It is difficult to be sure how Kevetrin is priced in, but, Brilacidin has substantially derisked this investment. I don't view it as much of a gamble even though nothing is guaranteed in the market.





In Reply to 'p53'
Caution required on Kevetrin certainly. At this point just searching for correct dosing,with hope to go on, some science, but mostly hopes. It is still so early.

Let's take the last published report about the vanishing spleen lesion. Lower in the article it says the patient's CA125(tumor marker) continued to rise, suggesting that change in ascites and spleen lesion was telling only part of the story.

Many here are gambling that there will be a payoff, and the stock has risen for quite a while.It is surely a gamble though.

Take away Kevetrin and how much will B and Prurisol be worth? Hard to be sure.




govorchin

02/12/15 8:20 PM

#91405 RE: To infinity and beyond! #91401

the persons conducting the trial wanted her to stay. must have thought they could help her. leo said something about not being able to change dose etc. have to stay with the rules.

my sister in law has ovarian cancer with the ca125 serum marker. it fluctuates. her doctor does not change protocol at first sign of increase.

i feel there is more to this story.

gov

slcimmuno

02/12/15 8:36 PM

#91407 RE: To infinity and beyond! #91401

Brilacidin is worth much more right now than K or P.... think you'd benefit from reading up on recent Big Pharma activity in the ABX space. With the results we have in hand, not to mention all the earlier PYMX clinical work being advanced CTIX (a true platform, multiple compounds), we're standing at the head of the line just waiting for the right partner to ask us to the Big Dance..... Choosing to be picky, playing hard-to-get, can be a very good thing.

thefamilyman

02/12/15 8:52 PM

#91411 RE: To infinity and beyond! #91401

Apparently, the presumption has always been that an increase in CA125 is bad and indicates a growing or metastizing tumor. On the other hand, it has been speculated (by me) that an increase in CA125 instead indicates an increase in the body's tumor fighting response. As to the increase in CA125 cited in the example below, I further postulate that it represents an increase in the body's tumor fighting response that was caused by Kevetrin.

Is my theory flawed? If so, please specify how and why you think that to be the case.

Let's take the last published report about the vanishing spleen lesion. Lower in the article it says the patient's CA125(tumor marker) continued to rise, suggesting that change in ascites and spleen lesion was telling only part of the story. - p53

cascott

02/12/15 9:34 PM

#91416 RE: To infinity and beyond! #91401

P53,
Didnt you hear of the research into p53 which supports CTIX research concerning P53...should read it and start to believe it, you know, your name and all....
:)


http://www.healthcanal.com/cancers/60134-iu-researcher-identifies-novel-pathway-that-solid-tumor-cancer-cells-activate-for-growth.html

Drano

02/12/15 11:09 PM

#91430 RE: To infinity and beyond! #91401

Dr. p53, as a physician surely you know that there are other things that can make the CA-125 reading rise.

If you don't, please read the surprisingly good wikipedia article on it.

We have no way of knowing what caused the CA-125 reading, especially as several articles point out that different labs with different procedures can get results that vary significantly, and that this is one factor that makes the reading sometimes unreliable.

We're going to have to wait for the data before we can say anything that isn't just speculation about this.

tduggan

02/12/15 11:40 PM

#91438 RE: To infinity and beyond! #91401

Take away Kevetrin and how much will B and Prurisol be worth? Hard to be sure.



Take away both K and P, and B across a broad spectrum still holds the possibility of better returns than any other equity I'm aware of.