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DewDiligence

01/27/15 1:49 PM

#186654 RE: ilpapa #186653

Have you opined on the CAR-T safety issue?

Not explicitly; however, it’s pretty clear that messing around with the immune system is a tricky thing to do. It would be astonishing if CAR-T and related technologies did not come with challenging safety issues.

poorgradstudent

01/27/15 2:24 PM

#186657 RE: ilpapa #186653

CAR-T / Safety:

I would be mindful of CNS adverse events.

DewDiligence

02/19/15 3:31 PM

#187665 RE: ilpapa #186653

CAR-T overview (from CEO of Unum Therapeutics) with emphasis on safety:

http://lifescivc.com/2015/02/better-living-through-t-cells/