Wynns...not sure of current status but it is known that they've been taking that aspect into consideration for at least the last 4 yrs...this shows the incorporation of NHM into gQD's as being feasible & it might be reasonable to presume there has been progress made into effective NHM compositions since this 2010 abstract was published....here's a few quotes on that: "Blinking as a function of shell thickness for different on-time fractions and shell composition........ We reported previously that for biological imaging or other applications for which a ‘less toxic’ surface chemistry was desired, the outermost CdS monolayers could be replaced with non-heavy-metal-containing ZnS layers" [note; Zinc shells were found to be less effective at non-blinking than CdSe in this study] "4. Conclusion. Studies are underway, with some initial results already reported,[4] to better understand the underlying mechanism(s) for these remarkable properties and to extend the approach to other core/shell systems, and, ideally, to more ‘bio-compatible’ NQD compositions. To this end, we are investigating giant-shell systems based on InP and ZnSe." http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943988/