Replies to post #81752 on Innovation Pharmaceuticals Inc (IPIX)

[biodoc]

Absolutely. Two stage total knee arthroplasty with hardware removal, antibiotic spacers, IV antibiotics, PO antibiotics, and eventual revision is probably the best case scenario. I'm sure you've seen others where attempted shortcuts turned into nightmares for everyone, with the patient suffering the greatest nightmare. Two stage revision is nightmare enough for any patient.

I mentioned potential perioperative use of Brilacidin in late August. Happy to see it could be a reality. From 67280:

I think the best perioperative opportunity with brilacidin is for orthopaedic cases where hardware is inserted. Total joint replacements come to mind as these are absolute nightmares when they get infected. Hardware coatings and/or mixing brilacidin with cement (methyl methacralate) might be considered. Also, I think a good case can be made for using brilacidin with other ortho cases where hardware (plates, screws) is inserted.