It's best to mess with companies that actually make something and have potential. The companies that are on the OTC and don't have a real product to sell don't have believers that will try to time things getting in and selling out, constantly trying to play the stock. Without a following like this, the stock would take a dive, the manipulators would end up with almost all the stock that is moving - and no one would want to buy it back for a while (until a new batch of fools is generated - usually a year+) because of being burned.