“We are using scalable processes so that we can rapidly transfer synthesis to kg-scale production, which we believe will be sufficient to contain the spread of the current Ebola epidemic,” said Anil R. Diwan, PhD, President and Chairman of the Company, adding, “We believe that the collaboration with USAMRIID will enable timely testing of our candidates in an effort to rapidly zero in on a final drug candidate against Ebola.”
Help me understand the science at a level I can handle.
As I understand it there is a base known as a micelle or micelles to which a ligand or ligands must be added, in the same sense that one adds different flavors to water to make different versions of Koolaid....although I expect that the process of combining the materials is a touch more complicated. Do I have that correct?
I am also of the understanding that NNVC somehow generates the micelles themselves and the ligands are provided by an outside source. True?
In the above quote the co-founder, President and Chairman of NNVC indicates that the company is using scalable processes that, should the drug under development prove effective, quantities would be able to be manufactured rapidly enough to contain the current Ebola epidemic.
Please help me understand how he can be so confident in these purported scalable processes when it took what seemed like forever to muster the 200grams of Flucide to be provided for the tox test, a quantity that according to the company itself is less than a tenth of what is needed for a full test.
Does/did the company not have the micelles necessary "in stock" to get this done sooner?
Was the delay a function of the inability of the ligand supplier to provide the needed material on a timely basis?
Or did the "scalable process" used to combine the materials fail to perform as desired?
In the absence of clear answers to those questions I don't know how I can justify a belief in this:
“We are using scalable processes so that we can rapidly transfer synthesis to kg-scale production, which we believe will be sufficient to contain the spread of the current Ebola epidemic,”
It SOUNDS FANTASTIC, but the pace at which the Flucide tox samples were produced makes it hard for me to accept.
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