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geocappy1

10/28/14 9:08 AM

#195228 RE: Protector #195226

Although your simulation may be very accurate, I find today's discussion very interesting. There was definitely a statement by Shan regarding 600+ patients vs previous 400+ patients. I too did not deduce this correctly. If 50 were from ISTs that leaves 150 for Sunrise trial which were dosed with Bavi and 150 not dosed with Bavi (randomization) or total enrolled 300.

This would also line up with 1st and 2nd looking in Spring and 4th quarter respectively. Assuming a slower w start to enrollment we could have 125-175 for 1st lookin and 275-300 for 2nd lookin.