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Rawnoc

09/13/14 5:52 PM

#98716 RE: daBoze #98715

I agree; forget those pesky red tape details that have held back NNVC for 9 years. Let NNVC go right in now!

Also, I think my ow recipe of 2 parts diet Sprite and 1 part Tabasco will kill the virus too. Think I can partner with NNVC and start shooting up patients with my secret sauce? Both of my ingredients are patented and go great with nachos.

robi-1-kenobi

09/13/14 6:15 PM

#98718 RE: daBoze #98715

If the Ebola patients in Liberia are likely to die, I don't see the necessity to do animal studies. Man is an animal. A dying man is an apt test subject. Enough bureaucratic nonsense.


daBoze - This is not the view of WHO or ethicists in this case (although I would think that maybe they would feel differently in cases of 100% death rates).

There is about a 50% chance of a person dying of this version of Ebola. What if every company and research group took it upon themselves to "just try it out - they are likely to die anyway" and the death rates increase, instead of go down.

I am sure you can see that this could turn into a circus fast.
And it won't reflect favorably on companies trying to shortcut the system (without even GLP Toxicity done, let alone human clinical Phase I trials for safety).

"First, do no harm" provides basis for the Hippocratic Oath.

There are multiple problems that could arise.
1. More people could die.
2. People could be given false hope of a potential cure and avoid therapies with actual benefit.
3. Distractions of medical personnel on not even minimally tested medicine whose time could be better spent on known supportive treatments and medicines with more evidence of potential to work.

There are also possible benefits - but the first medicines that should be tried first are those further in development with more animal study data.

NNVC has to do the work - there are no shortcuts in the real world (unless the real world collapses). That is why I am frustrated with the lack of progress and lack firm communications of timelines on the GLP Tox front.
And I don't want them to miss the FluCide opportunities. They need to GET IT DONE.