Replies to post #68712 on Innovation Pharmaceuticals Inc (IPIX)

[thefamilyman]

My thoughts exactly...

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Lilpunch said...

I wonder if this huge gap from 215mg-350mg dosage possibly be leaning towards being the final cohort in phase 1????

[rule_rationale]

Didn't Leo state in the presentation that the medical staff had implemented some pre-treatments to deal with some grade 2 events in earlier cohorts. Since that implementation, they have seen nothing above grade 1. This gave the review board confidence in allowing a typical dose escalation when no grade 2 events occur.

I wonder how long it will be until the trial is halted under recommendation from the review committee for immediate advancement into phase II/III?

[petemantx]

I would say just the opposite. They have been seeing so little side effects since the 100 unit cohort that they realize they can jack the dose up considerably and still be most likely to have no side effects.

Who was it that said they wondered if we would reach an MTD very early last year? I think it was the lady Dr. associated w/ CTIX.

Congrats to all the longs that stayed the course. Your loyalty and belief in CTIX looks like it is going to pay off in spades.