No, I'm pretty sure margins will remain minimal. As volume increases total dollar profit will go up but not margins. Royalties should start showing improvement, keep in mind that Q1 was the first full quarter of herceptin sc sales by roche. There is a 4.5 month lag in the reporting of royalties. In a few quarters I think that bulk sales figures will help determine estimated royalties sooner than waiting for roche to report.
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