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drkazmd65

08/04/14 2:50 PM

#6207 RE: mogman #6206

I hadn't heard of the company that makes that experimental serum before the other day mogman. They are:

http://mappbio.com/

And appear to be a small pharma company in San Diego that specializes in developing monoclonal antibody treatments for infectious diseases. They've got development stage (pre Phase I clinical testing) treatment candidates for several viral and for a couple of bacterial-derived toxins on their product development list - including ZMapp for Ebola virus.

They had a flier out last Summer (via work with USAMRIID) descibing some of the positve aspects of this drug candidate on Ebola in Monkeys:

http://www.leafbio.com/PettittAug2013.pdf

Sounds promising as they saw a ~40% recovery in symptomatic monkeys - but the use of this drug in this situation was unusual in humans. I certainly hope it does work - and that it can be produced in quanity by the company IF it does.

As regards CVM's potential use of the LEAPS system - as I said - it might work very well once the system is 'tuned' to working with Ebola. But - LEAPs is much further behind where it appears that ZMapp is for use in general.

And with the company currently resource limited and focused on H&N Cancer and HPV treatments using the Multikine product - I don't see that end advancing much unless a lot of time, money and resources are thrown at it.