Can MANF be crystallized and does the molecular weight/size of the protein allow such a thing? And does MANF need to be localized to work or can it travel throughout the circulatory system to find its way to where it is needed? Do you know the answers to these questions?
And right now, there is only one company that has the approved and advanced technology to do inhaled meds. That would be Mannkind's technosphere. I have been reading up on it and looks like a possible game changer in how medications are taken. Their first approved drug, inhaled insulin called Afrezza, is on the deck. Let's see how it does when launched early next year.
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