Metastasis, the strategy adopted by tumor cells to transform into an aggressive form of cancer, are often associated with a gloomy prognosis. Managing to block the metastasis or, even better, prevent their formation would be a giant step towards the fight against cancer. Researchers at Université catholique de Louvain (Belgium) successfully performed this world first on models of human tumors in mice. The results of their study are published online on 24 July in the journal Cell Reports.
The work by Professor Pierre Sonveaux's team, at Université catholique de Louvain's Institute of Experimental and Clinical Research (IREC), succeeded in pinpointing a family of pharmaceutical compounds whose action prevents the appearance of tumor metastasis. The researchers achieved this tour de force by studying the mitochondria in tumor cells. These organelles are considered as the cells' power station. But when their functioning is altered, as the UCL researchers observed in tumor cells, the mitochondria can promote cell migration, thus leading to the formation of metastasis.
Paolo E. Porporato, a post-doctoral researcher, and other young researchers in Professor Pierre Sonveaux's team, examined the molecular mechanism responsible for the mitochondria's ability to promote metastasis. They succeeded in showing that, under certain conditions, the mitochondria produce more free radicals known as superoxide ions (O2.-). It is this overproduction of superoxide that leads to the formation of metastasis and, consequently, the growth of a tumor.
Involved in other human pathologies such as Parkinson's and Alzheimer's disease, the production of superoxide by the mitochondria can be blocked by very specific antioxidants such as MitoTEMPO. Used in models of murine and human tumors, these compounds turned out to be very efficient at blocking the migration of tumor cells and preventing the spontaneous formation of human tumor metastasis in mice!
This research was conducted within the framework of projects mainly financed by an ERC Starting Grant, which Pierre Sonveaux obtained in 2009, and support from the F.R.S.-FNRS, Télévie and the Fondation contre le Cancer. The discovery of a treatment capable of blocking the mechanism responsible for the formation of metastasis and the existence of a family of promising compounds, is encouragement for their future assessment in a clinical study that aims to validate a preventive treatment against tumor metastasis.
Dr. Leon Coldwell has been stopped by the Federal Government in his great strides in curing cancer.
“Since all 7 siblings of my mom had cancer, as well as my grandmother dying of cancer, and even my father and stepfather dying of cancer I can tell you that Im sure no one else has the amount of experience with cancer that I have. I have seen it as family member, son and grandson from the start until it killed my relatives.
In my time I have seen over 35,000 patients and have had over 2.2 million seminar attendees that have written to me, sending in their comments and life stories. I have over 7 million readers of my newsletters and reports. I am the doctor that has, in the opinion of leading experts, the highest cancer cure rate in the world. In fact, I am convinced I could cure at least 90% of all cancer patients if I had the legal platform to work with these people the “Dr Coldwell Way.” As long as the patient is willing and still able to do whatever it takes and has no surgery, chemotherapy or radiation, there is no reason Cancer cannot be cured in most people.
I am sure I could cure them within weeks or a few months. But since the law and the ones that make money on your suffering and even death, dont allow me to treat you the way I know would produce results, I legally cannot even tell you what to do or not to do. That’s how the medical profession and pharmaceutical industry protects their Trillion Dollar Cancer Industry. They “make politicians install laws that kill citizens or at least make them sick, and laws that make sure they cannot be cured. They can only be treated to more illness and eventually death by the medical profession with toxic, dangerous and murderous treatments.”
Cancer Profit & Politics - Jesus is Savior - http://www.jesus-is-savior.com/Health_Concerns/cancer_profit.htm Dr. Stanislaw R. Burzynski, M.D., Ph.D., felt the full weight of just such an appearance. He was refused research money and raided by the 666 FDA, which seized by lucifer ... God Bless
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