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07/08/14 8:36 PM

#115352 RE: elichen #115348

elichen The drug is administered orally.


BIO-MD opioids are bioactivated molecular delivery systems. When administered orally, trypsin in the gastrointestinal tract releases the amino acid portion of the prodrug and provides the initial step in the process of opioid drug release. The pharmacokinetic profile is controlled by a subsequent reaction within the molecule itself that releases free opioid.