Replies to post #102907 on Amarantus Bioscience Holdings Inc (AMBS)

[Driven30]

• Initiate Phase 2b Clinical Trial (1H/14)

Regarding the above milestone. If I remember correctly, during the last conference call, didn't Dr. Lowe state Eltoprazine trials wouldn't start until late 2014-early 2015?

[Driven30]

Actually I was mistaken. This is part of Dr. Lowe's response to a question about a MANF IND for Parkinson's.

" So, investors shouldn’t think we’ve abandoned the PD at all. And then I think as the IND type data starts emerging we’ll have a much clearer idea of exactly how this molecule should be applied. And I would imagine that somewhere in mid to late 2015, something like that, would be where we’d be starting to dialogue with the FDA about how a clinical study could look, and should look. "

I'd still like to know when they stated they will initiate the Eltoprazine 2b trial in 1H/2014? I can't even imagine what the stock price will be when that PR hits.

[joboggi]

The milestones have come and gone, for the most part, with nary a pr, except for WS.

see the linked post for details. Of course, some of the milestones are noted for the second half.

[joboggi]

Current Milestones and Catalysts

LymPro
• Pilot clinical performance data (1H-14);
• Retrospective / prognostic 9 year patient record clinical study (1H-14);
• Clinical Performance studies to support CLIA registration (1H-14);
• Commercial Launch as a Laboratory-Developed Test (“LDT”) under CLIA (2H- 2014);

The first three are going to happen in a couple of days so that is close enough.

Eltoprazine
• Evaluate best indication for commercial development (1H/14)
• Initiate Phase 2b Clinical Trial (1H/14)

As per the last taped conference the first patient get the drug as the end of 2014.

MANF
• Retinitis Pigmentosa: functional genetic mouse model (1H-14)
• Parkinson’s disease: CED delivery data w/Renishaw (1H-14)
• Preliminary systemic toxicology (PK/PD relationship) (1H-14)
• Wolfram Syndrome enablement (Diabetes)

I am not sure what these milestones refer to. We knew before 2014 that Fumi would be studying MANF in WS. If the first was released I did not see that. The second was not released nor was the third.