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biomaven0

06/04/14 5:29 PM

#178834 RE: DewDiligence #178832

>>sensitivity of Botox efficacy in migraine to the precise placement of the multiple injection points?

I wouldn't read too much into that claim of precise placement - could just be noise. Botox doesn't work on some people and does on others (there have been recent claims of a biomarker) and there is also a significant placebo effect here. So lots of noise in general.

Or it could be that you need to inject fairly close to the various branches of the trigeminal nerve.

Someday a brave neurologist will inject into a patient's sphenopalatine junction (at back of the nasal passage) and (I would predict) get great results.

Peter