Friday, March 28, 2014 12:02:33 PM
DL: Absolutely. The cell cycle hypothesis of Alzheimer's disease is an exciting, breaking story. Some key investigators—one being David Holtzman at Washington University School of Medicine in St. Louis—are digging into this. It's slow to be accepted because it breaks the dogma that neurons are essentially postmitotic (no longer capable of producing two new nuclei in cell division). But we think something is going on in this respect. The phenomenon is reflected in the peripheral blood lymphocyte population, which may be a surrogate for neuronal activity. The LymPro test is based on this.
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