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jq1234

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jq1234

Re: Protector post# 169425

Tuesday, 03/25/2014 7:04:44 PM

Tuesday, March 25, 2014 7:04:44 PM

Post# of 346050
>> Under your assumption why would they even do a clinical trial with two arms if the results would per definition follow : More is Better.

You do two arms to see risk (AEs) vs benefit (efficacy). There was dose response AE wise (more AEs for 3mg/kg arm over 1mg/kg arm, and over placebo arm), but there wasn't one efficacy wise. One of main reasons people argued about data inconsistencies BEFORE the company actually announced that was placebo arm had more AEs over 1mg/kg arm which didn't make any sense. Dose response is important metrics in evaluating clinical trial data.
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