Rock Creek Pharmaceuticals Inc. (fka RCPIQ)

[Buddhahead]

Anavax, cancer, neuropathic pain---NEW YORK, Feb. 26, 2014 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. ("Anavex" or the "Company") (OTCQB:AVXL) today announced that a research article in the current issue of peer-reviewed scientific journal Molecular Pain reveals a new opportunity for the Company's anti-cancer and neuropathic pain compounds. The article describes that sigma-1 receptor (S1R) modulation prevents neuropathic pain and mitochondrial abnormalities induced by the chemotherapy drug paclitaxel.

Paclitaxel is a first-line anti-tumor agent that frequently produces neuropathic pain, for which no treatment is available. The lifestyle of patients receiving paclitaxel can be severely impacted and the problem is compounded by the lack of efficacy and frequent incidence of side effects associated with currently available treatments for pain. There is an important therapeutic opportunity for drug candidates that simultaneously fight cancer and prevent pain. Research firm GlobalData estimates the global neuropathic pain market alone will reach $6.5 billion in 2015. This growth will be supported by the increase in the aging population.

"These recent findings validate our pipeline beyond the area of Alzheimer's and neurological diseases and expand Anavex's opportunity to address diseases with significant markets," said Christopher U. Missling, PhD, President and Chief Executive Officer of Anavex. "The unique synergistic mechanism of action of the sigma-1 receptor modulators support further investigation of our existing drug candidates involved in both cancer and neuropathic pain activity."

Article at:
http://online.wsj.com/article/PR-CO-20140226-907754.html

Also,----
"NEW YORK, March 19, 2014 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. ("Anavex" or the "Company") (OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, diseases of the central nervous system (CNS) and various types of cancer, announced today that it has closed, as previously announced on March 13, 2014, the private placement of $10 million in principal amount of convertible debentures with several institutional and accredited investors, including U.S. and international healthcare funds. In addition, the investors received warrants to purchase up to approximately 66.7 million shares of common stock in the aggregate.

The funds will be used to initiate a Phase 1b/2a clinical trial of ANAVEX PLUS and advance its product portfolio. ANAVEX PLUS is a promising, potentially novel combination drug for Alzheimer's disease that combines ANAVEX 2-73 with donepezil (Aricept®), the world's best-selling Alzheimer's drug. "

Article at:
http://www.globenewswire.com/news-release/2014/03/19/619478/10073221/en/Anavex-Successfully-Closes-10-Million-Financing-to-Initiate-Phase-1b-2a-Alzheimer-s-Clinical-Trial.html