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Re: NNVClover post# 48498

Monday, 03/17/2014 9:12:16 PM

Monday, March 17, 2014 9:12:16 PM

Post# of 146295

PEG is one of the safest things known to man.
PEG-irinotecan would be one example of a not so safe PEG drug. You can add PEG to anything. PEG-interferon is the most commonly used drug. It is quite toxic. PEG does reduce peak blood levels of drug which lowers toxicity. It's a great invention for biotech based drugs and increasingly Nektar and Enzon (the PEG companies) have been able to attach them to small molecules. It's just a delivery tool. PEG by itself does nothing--it's inert pharmacologically.



And that is one reason for FDA tox testing!

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