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Post# of 252412
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Alias Born 07/18/2006

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Saturday, 03/15/2014 2:11:05 PM

Saturday, March 15, 2014 2:11:05 PM

Post# of 252412
Dew, as you know Geron's only product Imetelstat had their IND placed on full clinical hold because of LFT abnormalities noted in their ET trial and their MM trial (ongoing MF trial so far not affected but IND clearly is). None of these liver abnormalities bet Hy's law. Can you comment on how long these holds usually take to resolve and the severity of this FDA action and whether it carries a bad prognosis for the Imetelstat program in general which so far actually seems to be showing positive effects in MF (with unknown effect in AML and MP disease in small arms ongoing at Mayo Clinic) Thanks and regards, bp

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