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Thursday, March 13, 2014 12:10:40 AM
The amphiphilic polymeric micelles, which I believe similar to what NNVC uses, are discussed. Overall this paper, coupled with the chapter on Nanoviricides in the CRC publication Bionanotechnology II ISBN -10: 143980463X makes me more comfortable with both the envitable scaleup success and the likelihood of low toxicity.
It sounds like there could be a need to check the effect of repeated or extended dosing periods. But overall, not too bad. Nothing jumps out as an oh crap, thats a bummer!
Thanks a lot for finding this very recent work published in the International Journal of NanoMedicine on February 20th of this year!
I have been mostly focused on NNVC's animal testing results to date to give me confidence. Some of the detail in the assembly and issues surrounding the actual materials themselves is rather facinating. I can follow much of it, but I lack enough fluency in specific areas to really bear down on it as I would like.
Thanks again!
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