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Tuesday, 03/04/2014 12:40:23 PM

Tuesday, March 04, 2014 12:40:23 PM

Post# of 48316
Just got off the phone with Oncosec and was speaking with Patrick.They are going to add PD-1 to there IL-12 in the phase IIb trial.This to them is bigger than ORPHAN status in MCC because of the potential groundbreaking results.I asked him if it was approved by the FDA or is there a loop hole to adding a PD-1 mid Phase which he was unsure and will get me the answer, but they are moving forward with this and he believes it's because of how safe our trials with IL-12 have been.....AND to give him credit and one o there scientists for those who do not understand how IL-12 works with PD-1 and why this is huge...Here it is! If you are playing whack a mole and the IL-12 would represent the hammer..The cancer can hide which is why IL-12 would max out at a 60%/70% objective response...Well your PD-1 would be your Moles making them pop there heads out from hideing.Hence "whack a mole" so the PD-1 makes the mole or cancer treatable or appear and the IL-12 the "hammer" whacks the chit out of the previously hidden cancer...Giving a potential response rates probably of the likes no one has ever seen..Which is why Oncosec feels this is more important to this company than any catalyst this year!...ONCS

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