I wouldn't read JAK1 failure in lupus into psoriasis that much as there was POC clinical data from INCY's JAK1 specifically for psoriasis. Not sure about UC study hold though as there was POC clinical data from PFE's pan-JAK tofacitinib in UC - currently in ph3. Lupus still is a tough indication, as far as I know, this would have been the first POC clinical data in lupus if successful.
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