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Re: iwfal post# 174574

Thursday, 02/20/2014 2:28:59 PM

Thursday, February 20, 2014 2:28:59 PM

Post# of 253355

PRAN is a good example of why companies run such non-informative ph ii's—because they can't easily fail and can be spun positive easily.

From a design standpoint, PRAN’s HD trial was rather like a typical phase-1b/2a PoC study—not a trial intended to inform an educated go/no-go decision for advancing to phase-3.

Among the various arguments promulgated by PRAN longs, the one I find most lacking in merit is that the HD program has conclusively been shown to be phase-3-ready.

“The efficient-market hypothesis may be
the foremost piece of B.S. ever promulgated
in any area of human knowledge!”

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