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Re: iandy post# 174408

Tuesday, 02/18/2014 4:06:18 PM

Tuesday, February 18, 2014 4:06:18 PM

Post# of 252227

PRAN—First off you use Bonferroni corrections for multiple pairwise comparisons...

Given the huge number of secondary endpoints*, a bona fide use of Bonferroni corrections would have made the statsig p-value threshold for any given endpoint vanishingly small and nothing would have come out as "statsig."

*There were 672 shots on goal according to @JohnTuckerPhD on Twitter; I’ve cut this number to 336 insofar as it would not be impressive to show a “statsig” effect on some metric at the low dose but not the high dose.

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