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Wednesday, 02/12/2014 9:41:13 AM

Wednesday, February 12, 2014 9:41:13 AM

Post# of 130502
Recent Manf/Armet therapeutic research for genetic skeletal diseases:

http://hmg.oxfordjournals.org/content/early/2013/08/15/hmg.ddt383

"We demonstrate that Armet and Creld2 are genotype-specific ER stress response proteins with substrate specificities and that aggregation of mutant matrilin-3 is a key disease trigger in MED that could be exploited as a potential therapeutic target."

What role to do ARMET and CRELD2 play in genetic skeletal diseases?


http://mikebriggs1910.wordpress.com/research-overview-2/ongoing-projects/