Pacific Biosciences of California Inc (PACB)

[Paulieme]

David Glazer
Shared publicly - Today- 9:43 AM Great use of Google Cloud for genome assembly. (If you don't know what the jargon means, this is about putting together a 3-billlion-piece jigsaw puzzle, out of random chunks of a few hundred-to-thousand pre-assembled pieces, without looking at the picture on the cover.)

Pacific Biosciences collaborated with Google to leverage the Google Cloud Platform for the most computationally intensive part of the assembly pipeline. In a single day, the pipeline executed 405,000 CPU hours to align the long reads to each other. These data ... resulted in a 3.25 Gb assembly with a contig N50 of 4.38 Mb, and with the longest contig being 44 Mb. This represents over an order of magnitude better N50 than the most recent reference-guided assembly ... on the same sample, which had a total assembly size of 2.83 Gb and a contig N50 of 144 kb. https://plus.google.com/+DavidGlazer/posts/7m1T8EXPSYV#+DavidGlazer/posts/7m1T8EXPSYV