NanoViricides Inc. (NNVC)

[BonelessCat]

Because it is part of the final toxicology work and not part of the efficacy and proof of concept studies. Using the final form of the drug, the toxicology is performed across 3 species to determine a safe starting point for the first dose and to get a range of dose possibilities for the escalation, several possible highest doses. They use the most sensitive species outcomes to determine a safe starting dose. Then they examine the pharmacokinetics to see how long the drug remains in the system for each species and how each species processes and eliminates the drug to get an idea of cross species differences. This also gives insight into what might be anticipated as problems especially if each species processes and eliminates a drug quite differently. None of this can be done earlier.