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Re: pollyvonwog post# 173437

Thursday, 01/30/2014 1:50:51 PM

Thursday, January 30, 2014 1:50:51 PM

Post# of 253269
(TEVA/MNTA/MYL)—I take issue with the notion that thrice-weekly Copaxone truly represents an “improved dosing regimen.” Inasmuch as 7 is not divisible by 3, a thrice-weekly dosing schedule is suboptimal from a pharmacokinetic standpoint and is only marginally more convenient.

If Teva had conducted a large head-to-head trial of thrice-weekly Copaxone vs daily Copaxone, the thrice-weekly arm would probably have incurred a higher rate of AEs. However, such a trial will never be run by Teva.

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