I dont know if that's as good as it sounds. There is an issue here. Since the median time to chemo is 28m and the median OS is 32m, is it possible that Xtandi was somehow masking the progression of cancer artificially?
I know that the median OS after Xtandi is not 4m but it does not look anywhere close to 21m either as reported in recent (e.g., docetaxel +/- dasatinib) studies even without the newest therapies.
If the patients have started the chemo and then the other therapies earlier (say at radiographic progression), would that have made a difference in OS?
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