Avid Bioservices Inc (CDMO)

[exwannabe]

Sounds lite Cotara is what CLSN is trying to do?

Other than they are both trying to "target" existing agents, they are not really that close.

Cotara is using a mab to direct the radiation specifically to the cancer cells. Yeah, a little collateral damage, but not as much as in standard radiation treatment.

CLSN's thermodox is coating a chemo (doxyrubicin) with a fat. Then they heat the target up (via radio frequency ablation), that melts the fat off locally and delivers the chmo on the spot.

A closer comparison would be CLSN's potential competitor Sirtex. They take small radioactive spheres and deliver them via catheters to the target.

Conceptually, one would expect Cotara to work somewhat better, as the mab can navigate down to the cellular level and not just the general area that the other 2 treatments can accomplish.

I do agree with Wookie here, shame to see what sounds like a potentially valuable drug not be developed due to money.