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biotech jim

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biotech jim

Re: DewDiligence post# 172654

Tuesday, 01/14/2014 9:58:27 AM

Tuesday, January 14, 2014 9:58:27 AM

Post# of 252239
Does anyone know the MOA of MK-7622? It is the small molecule in an AD trial for cognitive enhancement, on top of the cholinesterase inhibitor donepezil.

http://clinicaltrials.gov/show/NCT01852110

Efficacy and Safety of MK-7622 as Adjunct Therapy to Donepezil in Participants With Alzheimer's Disease (MK-7622-012)

My suspicion is that it is a GABA alpha 5 subtype receptor inverse agonist.
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