Ariad Pharmaceuticals Inc fka ARIA

[ilpapa]

I've found the label and don't see a requirement to have failed other therapies. Could you direct me to the relevant passage?

Not trying to be disputative, BTW. just confused

Iclusig is a kinase inhibitor indicated for the:
• Treatment of adult patients with T315I-positive chronic myeloid
leukemia (chronic phase, accelerated phase, or blast phase) or T315Ipositive Philadelphia chromosome positive acute lymphoblastic
leukemia (Ph+ ALL).
• Treatment of adult patients with chronic phase, accelerated phase, or
blast phase chronic myeloid leukemia or Ph+ ALL for whom no other
tyrosine kinase inhibitor (TKI) therapy is indicated. (1)
These indications are based upon response rate. There are no trials verifying an
improvement in disease-related symptoms or increased survival with Iclusig.