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Re: Dr Jerry post# 48692

Sunday, 12/15/2013 2:20:04 PM

Sunday, December 15, 2013 2:20:04 PM

Post# of 403092
"If you look carefully at the data presented by Polymedix for Brilacidin in it's phase 2 study, its imperative to note that only Brilacidin in the high dose of 1.0 mg/kg day 1 + 0.35 mg/kg days 2-5
produced equal results at day 28 compared to daptomycin."


????????????????????????????


at 28 days...

Daptomycin - 98%
Brilacidin (high dose) - 95.6%
Brilacidin (low dose) - 95.7%

ABSSSI patients with MSSA or MRSA...

Daptomycin - 7 days of treatment
Brilacidin - 5 days of treatment

The reality of antibiotic resistance simply means there is a great need for new treatment options... Brilacidin does not have to beat Daptomycin to address a great medical need... it simply needs to be comparable and at 28 days in the p2a it certainly was at both high and low dose...
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