Amarantus Bioscience Holdings Inc (AMBS)

[Solantey]

MANF "Second Orphan" Process of Elimination

Gerald has spoken about several indications the company is researching pertaining to MANF: 1) Parkinsons, 2) Traumatic Brain Injury (TBI), 3) Retinits, 4) Diabetes (Wolfram's Syndrome), & 5) Ischemic Heart Disease. These are the indications most spoken of. Other indications less spoken of include: Strokes, Hearing, and Organ Transplants, and perhaps a few others. But, of the main 5 indications Gerald focuses on we know that "Retinitis" isn't the "second orphan" because it is already the "first orphan" we've publically identified. Of the remaining four we know that Parkinsons and Ischemic Heart Disease don't qualify because they are not rare enough to qualify with the FDA as an "orphan disease." So that leaves TBI and Wolframs (a rare subset of Diabetes). At the Conference in L.A. last Tuesday I asked Gerald if he thought TBI would qualify as an "orphan?" The answer he gave me was not definitive, but he seemed to show doubt whether it was rare enough to qualify as an "orphan." Thus, by process of elimination that only leaves us with "Wolfram's Syndrome." Gerald told us several months ago that he had the data for the second orphan in hand and would be announcing it soon, but we heard nothing. We got Retinitis, but no second orphan. Then in the CC two weeks ago he said the reason he hasn't made it public yet is because it is still in "negotiations." "Negotiations?" Retinitis wasn't delayed because there wasn't a Partner revealed when they released the data. Could it be that the "second orphan" data will not be released until we have finalized the Partnership that will go along with it? I THINK SO. I THINK IT WILL BE "WOLFRAM'S SYNDROME." I don't know who the Partner will be but according to Dr. Urano who has conducted the testing for Wolframs, finding a cure for Wolframs is the same as finding a cure for Type 2 Diabetes!! I THINK WE HAVE FOUND A SHORT CUT TO COMMERCIALIZING A BREAKTHROUGH TREATMENT FOR TYPE 2 DIABETES!! THAT COULD BE HUGE!

Posted by riskreturn168 on the Yahoo board.