GSK heart treatment fails in Phase III trial GSK's (GSK) darapladib treatment failed to reduce the risk of heart attack or stroke among chronic-heart-disease patients in the first of two Phase III trials. GSK acquired the rights to darapladib when it bought Human Genome Sciences for $3B in 2012. In the study of over 1,500 patients, darapladib was no better than a placebo in cutting the time prior to a heart attack, stroke or death. However, darapladib did bring about a reduction in some coronary events, although GSK didn't provide details. Analyst Savvas Neophytou expects GSK to take a writedown of £150M ($239M) in Q4 because of the failure of darapladib. Shares are -2.2% premarket
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