Biotech Values

[Summer2762]

Tracking the clonal origin of lethal prostate cancer

Even though the processes and the conclusions are hard to generalize, this is a very intriguing paper.

http://www.jci.org/articles/view/70354?key=4f436390394081ee2a50

Especially the following result

Surprisingly, these analyses revealed that the lethal clone arose from a small, relatively low-grade cancer focus in the primary tumor, and not from the bulk, higher-grade primary cancer or from a lymph node metastasis resected at prostatectomy.