Innovation Pharmaceuticals Inc (IPIX)

[Orion Nebula]

No doubt in my mind that the 3 scientists awarded the Nobel prize in Chemistry on Wednesday have had a great impact on the PolyM drug pipeline and perhaps on much of the work of Dr. Menon as well. They are US based but all 3 have multi national status. Their work was done in the 1970s and provided a new way to do chemistry on a computer. It was a tremendous breakthrough as they had to blend the great dilemma of Physics - the reconciliation of the very large (Newtonian Physics) with the very small (quantum physics). The computational system they developed allows scientists a way to understand interactions between thousands to millions of atoms according to the press release. The article I read has the following quote..."There are thousands of laboratories around the world using these methodologies both for basic biochemistry and for things like drug design."

I remember someone posting a short bio on the lead scientist for Poly and he extolled the virtue of the use of a supercomputer model for identifying the best drug candidates. Said it would not have been possible without it. It all goes to show the seemingly logarithmic advances that are occurring. The work of Martin Karplus, Michael Levitt and Arieh Warshel pushed drug development into a new era.