Innovation Pharmaceuticals Inc (IPIX)

[Truthbythought]

Could you clarify why you think 100 is the important dose? This goes back to a debate that happened a long time ago now. So long ago that I had forgotten the original predictions. I have an email into the Company to try to figure out why 100 is so important. My numbers (and I have reworked them many many times at this point and run them by others) indicate a much higher dosage is required (based solely on the mouse study numbers). I will not repeat the logic here since last time the topic was raised it appeared many on here were not very good at math. But lets just say it led me to believe that based on mouse tumor response data we had to be at a minimum above 150mg/m2 to see effects on tumors.

To put what to expect further into perspective - from what I can tell the mouse model showed slowed growth at 300mg/m2 administered 3 times a week and much more significant delay at 550mg/m2 administered 3 times a week. Add a second round at 550mg/m2 and you get the best of the predicted results.

I will concede that extended treatment at something above 150mg/m2 may also yield delay, but the drug we are dreaming of exists closer to 500mg/m2 dosing in humans.

Happy to be wrong, but so far no response from Leo.