Pacific Biosciences of California Inc (PACB)

[Paulieme]

Published: 3 October 2013---Using data generated solely from the Pacific Biosciences RS, we were able to generate the most complete and accurate de novo assemblies of E. coli strains. We found that the addition of other sequencing technology data offered no improvements over use of PacBio data alone. In addition, the sequencing data from the PacBio RS allowed for sensitive and specific calling of covalent base modifications. http://www.biomedcentral.com/1471-2164/14/675/abstract