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Post# of 252478
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Re: mcbio post# 165956

Wednesday, 09/04/2013 10:01:21 AM

Wednesday, September 04, 2013 10:01:21 AM

Post# of 252478
ARQL:

But, I have to lower my outlook on chances of success for P3 HCC trial now.



That's putting it pretty kindly isn't it?

If I'm not mistaken, there are zero prior data for efficacy at the 120 dose for HCC upon which we can extrapolate for the phase 3. I'm surprised that people are actually discussing this situation rather than running away screaming.

I don't think it's in the newbie rules but there's gotta be one added that says something like "Never bet on a phase 3 that is using a drug at a dose for which there are no prior data."

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